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Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism

INTRODUCTION: Cancer stem cells (CSCs) possess characteristics associated with normal stem cells, specifically the abilities to renew themselves and to give rise to all cell types (differentiation). It is assumed that induction of differentiation in CSCs would reduce their ability to form tumors. Wh...

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Detalles Bibliográficos
Autores principales: Yuan, Shuqiang, Lu, Yunxin, Yang, Jing, Chen, Gang, Kim, Sangbae, Feng, Li, Ogasawara, Marcia, Hammoudi, Naima, Lu, Weiqin, Zhang, Hui, Liu, Jinyun, Colman, Howard, Lee, Ju-Seog, Li, Xiao-Nan, Xu, Rui-hua, Huang, Peng, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606508/
https://www.ncbi.nlm.nih.gov/pubmed/26472041
http://dx.doi.org/10.1186/s13287-015-0174-2