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Development of novel real-time PCR methodology for quantification of COL11A1 mRNA variants and evaluation in breast cancer tissue specimens

BACKGROUND: Collagen XI is a key structural component of the extracellular matrix and consists of three alpha chains. One of these chains, the α1 (XI), is encoded by the COL11A1 gene and is transcribed to four different variants at least (A, B, C and E) that differ in the propensity to N-terminal do...

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Detalles Bibliográficos
Autores principales: Karaglani, Makrina, Toumpoulis, Ioannis, Goutas, Nikolaos, Poumpouridou, Nikoleta, Vlachodimitropoulos, Dimitrios, Vasilaros, Spyridon, Rizos, Ioannis, Kroupis, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606509/
https://www.ncbi.nlm.nih.gov/pubmed/26466668
http://dx.doi.org/10.1186/s12885-015-1725-8