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PDE/ODE modeling and simulation to determine the role of diffusion in long-term and -range cellular signaling

BACKGROUND: We study the relevance of diffusion for the dynamics of signaling pathways. Mathematical modeling of cellular diffusion leads to a coupled system of differential equations with Robin boundary conditions which requires a substantial knowledge in mathematical theory. Using our new develope...

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Detalles Bibliográficos
Autor principal: Friedmann, Elfriede
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606510/
https://www.ncbi.nlm.nih.gov/pubmed/26473028
http://dx.doi.org/10.1186/s13628-015-0024-8