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Physiological increases in lactate inhibit intracellular calcium transients, acidify myocytes and decrease force in term pregnant rat myometrium

KEY POINTS: Lactate is increased in myometrial capillary blood from women in slow or non‐progressive labour (dystocia), suggesting that it is detrimental to uterine contractions. There are no studies of the effect of lactate on the myometrium. In the present study, we have investigated its effects a...

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Detalles Bibliográficos
Autores principales: Hanley, Jacqui‐Ann, Weeks, Andrew, Wray, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606541/
https://www.ncbi.nlm.nih.gov/pubmed/26223765
http://dx.doi.org/10.1113/JP270631