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Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle
BACKGROUND: Rho kinase (ROCK) and myosin-light chain kinase (MLCK) are key enzymes in smooth muscle contraction. Previous data have suggested that ROCK contribution to human detrusor contraction is increasing with age. Here, we have analyzed the transcriptional expression of Rho kinase isoforms (ROC...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606542/ https://www.ncbi.nlm.nih.gov/pubmed/26468005 http://dx.doi.org/10.1186/s12894-015-0098-2 |