Cargando…

Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle

BACKGROUND: Rho kinase (ROCK) and myosin-light chain kinase (MLCK) are key enzymes in smooth muscle contraction. Previous data have suggested that ROCK contribution to human detrusor contraction is increasing with age. Here, we have analyzed the transcriptional expression of Rho kinase isoforms (ROC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kirschstein, Timo, Sahre, Theresa, Kernig, Karoline, Protzel, Chris, Porath, Katrin, Köhling, Rüdiger, Hakenberg, Oliver W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606542/ https://www.ncbi.nlm.nih.gov/pubmed/26468005 http://dx.doi.org/10.1186/s12894-015-0098-2

Ejemplares similares

Hyperpolarization-Activated Cyclic Nucleotide-Gated Non-selective (HCN) Ion Channels Regulate Human and Murine Urinary Bladder Contractility
por: Mader, Felix, et al.
Publicado: (2018)

Studies on Biological and Molecular Effects of Small-Molecule Kinase Inhibitors on Human Glioblastoma Cells and Organotypic Brain Slices
por: Hörnschemeyer, Julia, et al.
Publicado: (2022)

The sphingosine-1-phosphate/RhoA/Rho associated kinases/myosin light chain pathway in detrusor of female rats is down-regulated in response to ovariectomy
por: Zhang, Wei, et al.
Publicado: (2020)

Effects of Microbeam Irradiation on Rodent Esophageal Smooth Muscle Contraction
por: Frerker, Bernd, et al.
Publicado: (2022)

Rho-associated kinase and zipper-interacting protein kinase, but not myosin light chain kinase, are involved in the regulation of myosin phosphorylation in serum-stimulated human arterial smooth muscle cells
por: Deng, Jing-Ti, et al.
Publicado: (2019)

Novel Object Recognition in Rats With NMDAR Dysfunction in CA1 After Stereotactic Injection of Anti-NMDAR Encephalitis Cerebrospinal Fluid
por: Kersten, Maxi, et al.
Publicado: (2019)

The Regulation of Intestinal Mucosal Barrier by Myosin Light Chain Kinase/Rho Kinases
por: Jin, Younggeon, et al.
Publicado: (2020)

Dynamic Regulation of Myosin Light Chain Phosphorylation by Rho-kinase
por: Kaneko-Kawano, Takako, et al.
Publicado: (2012)

Rho-kinase mediates diphosphorylation of myosin regulatory light chain in cultured uterine, but not vascular smooth muscle cells
por: Aguilar, Hector N, et al.
Publicado: (2012)

Direct-Current Electrical Field Stimulation of Patient-Derived Colorectal Cancer Cells
por: Lange, Falko, et al.
Publicado: (2023)

Differentially Altered NMDAR Dependent and Independent Long-Term Potentiation in the CA3 Subfield in a Model of Anti-NMDAR Encephalitis
por: Blome, Roman, et al.
Publicado: (2018)

Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase
por: Lou, Sunny S., et al.
Publicado: (2015)

Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II
por: Murray, Ailish, et al.
Publicado: (2010)

Phosphorylation of Myosin-Binding Subunit (Mbs) of Myosin Phosphatase by Rho-Kinase in Vivo
por: Kawano, Yoji, et al.
Publicado: (1999)

Ardipusilloside-I stimulates gastrointestinal motility and phosphorylation of smooth muscle myosin by myosin light chain kinase
por: Xu, Zhili, et al.
Publicado: (2017)

Diffusion of myosin light chain kinase on actin: A mechanism to enhance myosin phosphorylation rates in smooth muscle
por: Hong, Feng, et al.
Publicado: (2015)

Status Epilepticus Enhances Depotentiation after Fully Established LTP in an NMDAR-Dependent but GluN2B-Independent Manner
por: Guli, Xiati, et al.
Publicado: (2016)

AMPA receptor antagonist perampanel affects glioblastoma cell growth and glutamate release in vitro
por: Lange, Falko, et al.
Publicado: (2019)

Rho Kinase's Role in Myosin Recruitment to the Equatorial Cortex of Mitotic Drosophila S2 Cells Is for Myosin Regulatory Light Chain Phosphorylation
por: Dean, Sara O., et al.
Publicado: (2006)

Berberine Depresses Contraction of Smooth Muscle via Inhibiting Myosin Light-chain Kinase
por: Xu, Zhili, et al.
Publicado: (2017)

Human Osteoblast Migration in DC Electrical Fields Depends on Store Operated Ca(2+)-Release and Is Correlated to Upregulation of Stretch-Activated TRPM7 Channels
por: Rohde, Marco, et al.
Publicado: (2019)

Inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide
por: Nalli, Ancy D., et al.
Publicado: (2017)

Association of the Myosin-binding Subunit of Myosin Phosphatase and Moesin: Dual Regulation of Moesin Phosphorylation by Rho-associated Kinase and Myosin Phosphatase
por: Fukata, Yuko, et al.
Publicado: (1998)

The Rho kinases I and II regulate different aspects of myosin II activity
por: Yoneda, Atsuko, et al.
Publicado: (2005)

Galvanotactic Migration of Glioblastoma and Brain Metastases Cells
por: Lange, Falko, et al.
Publicado: (2022)

Rho-kinase regulates tissue morphogenesis via non-muscle myosin and LIM-kinase during Drosophila development
por: Verdier, Valerie, et al.
Publicado: (2006)

NMDA Receptor-Dependent Metaplasticity by High-Frequency Magnetic Stimulation
por: Tokay, Tursonjan, et al.
Publicado: (2014)

Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs
por: Sharanek, Ahmad, et al.
Publicado: (2016)

Activation of G(12)/G(13) Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets
por: Klages, Birgit, et al.
Publicado: (1999)

Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway
por: Lv, Yanni, et al.
Publicado: (2020)

Increasing evidence of mechanical force as a functional regulator in smooth muscle myosin light chain kinase
por: Baumann, Fabian, et al.
Publicado: (2017)

Ageing influences detrusor contractions to prostaglandin, angiotensin, histamine and 5-HT (serotonin), independent to the Rho kinase and extracellular calcium pathways
por: Phelps, Charlotte, et al.
Publicado: (2023)

Vascular smooth muscle cell glycocalyx mediates shear stress-induced contractile responses via a Rho kinase (ROCK)-myosin light chain phosphatase (MLCP) pathway
por: Kang, Hongyan, et al.
Publicado: (2017)

Divergent modulation of Rho‐kinase and Ca(2+) influx pathways by Src family kinases and focal adhesion kinase in airway smooth muscle
por: Shaifta, Yasin, et al.
Publicado: (2015)

Enhanced RAGE Expression and Excess Reactive-Oxygen Species Production Mediates Rho Kinase-Dependent Detrusor Overactivity After Methylglyoxal Exposure
por: Oliveira, Akila L., et al.
Publicado: (2022)

MiR-31 Regulates Rho-Associated Kinase-Myosin Light Chain (ROCK-MLC) Pathway and Inhibits Gastric Cancer Invasion: Roles of RhoA
por: Chen, Zhuo, et al.
Publicado: (2016)

TNF causes changes in glomerular endothelial permeability and morphology through a Rho and myosin light chain kinase‐dependent mechanism
por: Xu, Chang, et al.
Publicado: (2015)

An MBoC Favorite: Cell contact–dependent regulation of epithelial–myofibroblast transition via the Rho-Rho-kinase-phospho-myosin pathway
por: Ivanov, Andrei I.
Publicado: (2012)

ZD7288 Enhances Long-Term Depression at Early Postnatal Medial Perforant Path-Granule Cell Synapses
por: Guli, Xiati, et al.
Publicado: (2012)

Distinct Effects of Stereotactically Injected Human Cerebrospinal Fluid Containing Glutamic Acid Decarboxylase Antibodies into the Hippocampus of Rats on the Development of Spontaneous Epileptic Activity
por: Frerker, Bernd, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_riq0fg3gptlu3pcsrmvq5bap7m