Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis

Astrocytes are key players in the progression of amyotrophic lateral sclerosis (ALS). Previously, gene expression profiling of astrocytes from the pre-symptomatic stage of the SOD1(G93A) model of ALS has revealed reduced lactate metabolism and altered trophic support. Here, we have performed microar...

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書目詳細資料
Autores principales: Baker, David J., Blackburn, Daniel J., Keatinge, Marcus, Sokhi, Dilraj, Viskaitis, Paulius, Heath, Paul R., Ferraiuolo, Laura, Kirby, Janine, Shaw, Pamela J.
格式: Online Artículo Texto
語言:English
出版: Frontiers Media S.A. 2015
主題:
Neuroscience
在線閱讀:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606544/
https://www.ncbi.nlm.nih.gov/pubmed/26528138
http://dx.doi.org/10.3389/fncel.2015.00410

因特網

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606544/
https://www.ncbi.nlm.nih.gov/pubmed/26528138
http://dx.doi.org/10.3389/fncel.2015.00410

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