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Apelin protect against multiple organ injury following hemorrhagic shock and decrease the inflammatory response

INTRODUCTION: Hemorrhagic shock (HS) result in multiple organ injury and inflammatory response that lead to death. The exact mechanism is not clear. Apelin is an endogenous ligand of orphan G-protein coupled receptor APJ. Apelin has anti-inflammatory effects on the release of inflammatory mediators....

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Detalles Bibliográficos
Autores principales: Soliman, Mona, Arafah, Maha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606580/
https://www.ncbi.nlm.nih.gov/pubmed/26539370
http://dx.doi.org/10.4103/2229-516X.165377