Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein–Coupled Bile Acid Receptors

Bile acids are well-recognized stimuli of glucagon-like peptide-1 (GLP-1) secretion. This action has been attributed to activation of the G protein–coupled bile acid receptor GPBAR1 (TGR5), although other potential bile acid sensors include the nuclear farnesoid receptor and the apical sodium-couple...

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Detalles Bibliográficos
Autores principales: Brighton, Cheryl A., Rievaj, Juraj, Kuhre, Rune E., Glass, Leslie L., Schoonjans, Kristina, Holst, Jens J., Gribble, Fiona M., Reimann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606749/
https://www.ncbi.nlm.nih.gov/pubmed/26280129
http://dx.doi.org/10.1210/en.2015-1321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606749/
https://www.ncbi.nlm.nih.gov/pubmed/26280129
http://dx.doi.org/10.1210/en.2015-1321

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