HMGB1 induction of clusterin creates a chemoresistant niche in human prostate tumor cells

Development of chemoresistance, especially to docetaxel (DTX), is the primary barrier to the cure of castration-resistant prostate cancer but its mechanism is obscure. Here, we report a seminal crosstalk between dying and residual live tumor cells during treatment with DTX that can result in outgrow...

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Detalles Bibliográficos
Autores principales: Zhou, Junmin, Chen, Xianghong, Gilvary, Danielle L., Tejera, Melba M., Eksioglu, Erika A., Wei, Sheng, Djeu, Julie Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606829/
https://www.ncbi.nlm.nih.gov/pubmed/26469759
http://dx.doi.org/10.1038/srep15085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606829/
https://www.ncbi.nlm.nih.gov/pubmed/26469759
http://dx.doi.org/10.1038/srep15085

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