Roles of the crotonyl-CoA carboxylase/reductase homologues in acetate assimilation and biosynthesis of immunosuppressant FK506 in Streptomyces tsukubaensis

BACKGROUND: In microorganisms lacking a functional glyoxylate cycle, acetate can be assimilated by alternative pathways of carbon metabolism such as the ethylmalonyl-CoA (EMC) pathway. Among the enzymes converting CoA-esters of the EMC pathway, there is a unique carboxylase that reductively carboxyl...

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Detalles Bibliográficos
Autores principales: Blažič, Marko, Kosec, Gregor, Baebler, Špela, Gruden, Kristina, Petković, Hrvoje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606968/
https://www.ncbi.nlm.nih.gov/pubmed/26466669
http://dx.doi.org/10.1186/s12934-015-0352-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606968/
https://www.ncbi.nlm.nih.gov/pubmed/26466669
http://dx.doi.org/10.1186/s12934-015-0352-z

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