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Multipotent luminal mammary cancer stem cells model tumor heterogeneity

INTRODUCTION: The diversity of human breast cancer subtypes has led to the hypothesis that breast cancer is actually a number of different diseases arising from cells at various stages of differentiation. The elusive nature of the cell(s) of origin thus hampers approaches to eradicate the disease. M...

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Detalles Bibliográficos
Autores principales: Bao, Lei, Cardiff, Robert D., Steinbach, Paul, Messer, Karen S., Ellies, Lesley G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606989/
https://www.ncbi.nlm.nih.gov/pubmed/26467658
http://dx.doi.org/10.1186/s13058-015-0615-y