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Associations between hepcidin and immune response in individuals with hyperbilirubinaemia and severe malaria due to Plasmodium vivax infection

BACKGROUND: Hyperbilirubinaemia (bilirubin >51.3 μmol/L) alone is not indicative of severe malaria, and the immune response underlying hyperbilirubinaemia remains largely unexplored. Liver damage associated with hyperbilirubinaemia may alter the expression of hepcidin, which regulates systemic ir...

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Detalles Bibliográficos
Autores principales: Mendonça, Vitor R. R., Souza, Ligia C. L., Garcia, Gabriela C., Magalhães, Belisa M. L., Gonçalves, Marilda S., Lacerda, Marcus V. G., Barral-Netto, Manoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607001/
https://www.ncbi.nlm.nih.gov/pubmed/26466783
http://dx.doi.org/10.1186/s12936-015-0930-x