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Layer-by-layer heparinization of decellularized liver matrices to reduce thrombogenicity of tissue engineered grafts

BACKGROUND: Tissue–engineered liver grafts may offer a viable alternative to orthotopic liver transplantation and help overcome the donor organ shortage. Decellularized liver matrices (DLM) have a preserved vasculature and sustain hepatocellular function in culture, but graft survival after transpla...

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Detalles Bibliográficos
Autores principales: Bruinsma, Bote G, Kim, Yeonhee, Berendsen, Tim A, Ozer, Sinan, Yarmush, Martin L, Uygun, Basak E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607069/
https://www.ncbi.nlm.nih.gov/pubmed/30873444