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Layer-by-layer heparinization of decellularized liver matrices to reduce thrombogenicity of tissue engineered grafts
BACKGROUND: Tissue–engineered liver grafts may offer a viable alternative to orthotopic liver transplantation and help overcome the donor organ shortage. Decellularized liver matrices (DLM) have a preserved vasculature and sustain hepatocellular function in culture, but graft survival after transpla...
Autores principales: | Bruinsma, Bote G, Kim, Yeonhee, Berendsen, Tim A, Ozer, Sinan, Yarmush, Martin L, Uygun, Basak E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Whioce Publishing Pte. Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607069/ https://www.ncbi.nlm.nih.gov/pubmed/30873444 |
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