Complexity of a small non-protein coding sequence in chromosomal region 22q11.2: presence of specialized DNA secondary structures and RNA exon/intron motifs

BACKGROUND: DiGeorge Syndrome is a genetic abnormality involving ~3 Mb deletion in human chromosome 22, termed 22q.11.2. To better understand the non-coding regions of 22q.11.2, a small 10,000 bp non-protein-coding sequence close to the DiGeorge Critical Region 6 gene (DGCR6) was chosen for analysis...

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Detalles Bibliográficos
Autor principal: Delihas, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607176/
https://www.ncbi.nlm.nih.gov/pubmed/26467088
http://dx.doi.org/10.1186/s12864-015-1958-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607176/
https://www.ncbi.nlm.nih.gov/pubmed/26467088
http://dx.doi.org/10.1186/s12864-015-1958-6

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