Rapamycin-enhanced mitomycin C-induced apoptotic death is mediated through the S6K1–Bad–Bak pathway in peritoneal carcinomatosis

Peritoneal carcinomatosis (PC) is the most common secondary cancerous disease, and more effective novel regimens are needed. In this study, we identified a novel combination treatment for PC, chemotherapeutic agent mitomycin C in combination with mTOR (mammalian target of rapamycin) inhibitor rapamy...

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Detalles Bibliográficos
Autores principales: Song, X, Dilly, A-K, Kim, S-Y, Choudry, H A, Lee, Y J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607229/
https://www.ncbi.nlm.nih.gov/pubmed/24901052
http://dx.doi.org/10.1038/cddis.2014.242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607229/
https://www.ncbi.nlm.nih.gov/pubmed/24901052
http://dx.doi.org/10.1038/cddis.2014.242

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