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Therapeutic stimulation of GLP-1 and GIP protein with DPP-4 inhibitors for type-2 diabetes treatment

Dipeptidyl peptidase-4 (DPP-4) inhibition is a new treatment for type-2 diabetes. DPP-4 inhibition increases levels of active GLP-1. GLP-1 enhances insulin secretion and diminishes glucagon secretion, in this manner reducing glucose concentrations in blood. A number of DPP-4 inhibitors are under cli...

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Detalles Bibliográficos
Autores principales: Sharma, Alok, Paliwal, Geetanjali, Upadhyay, Nisha, Tiwari, Archana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607261/
https://www.ncbi.nlm.nih.gov/pubmed/26473146
http://dx.doi.org/10.1186/s40200-015-0143-4