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Acetylome Analysis Identifies SIRT1 Targets in mRNA-Processing and Chromatin-Remodeling in Mouse Liver

Lysine acetylation is a post-translational modification found on numerous proteins, a strategy used in cell signaling to change protein activity in response to internal or external cues. Sirtuin 1 (SIRT1) is a central lysine deacetylase involved in a variety of cellular processes including metabolis...

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Detalles Bibliográficos
Autores principales: Kim, Sun-Yee, Sim, Choon Kiat, Tang, Hui, Han, Weiping, Zhang, Kangling, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607365/
https://www.ncbi.nlm.nih.gov/pubmed/26468954
http://dx.doi.org/10.1371/journal.pone.0140619