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Comparative Fitness of a Parent Leishmania donovani Clinical Isolate and Its Experimentally Derived Paromomycin-Resistant Strain

Paromomycin has recently been introduced for the treatment of visceral leishmaniasis and emergence of drug resistance can only be appropriately judged upon its long term routine use in the field. Understanding alterations in parasite behavior linked to paromomycin-resistance may be essential to asse...

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Detalles Bibliográficos
Autores principales: Hendrickx, Sarah, Leemans, Annelies, Mondelaers, Annelies, Rijal, Suman, Khanal, Basudha, Dujardin, Jean-Claude, Delputte, Peter, Cos, Paul, Maes, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607421/
https://www.ncbi.nlm.nih.gov/pubmed/26469696
http://dx.doi.org/10.1371/journal.pone.0140139