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The Effects of CFTR and Mucoid Phenotype on Susceptibility and Innate Immune Responses in a Mouse Model of Pneumococcal Lung Disease

Recent studies have reported the isolation of highly mucoid serotype 3 Streptococcus pneumoniae (Sp) from the respiratory tracts of children with cystic fibrosis (CF). Whether these highly mucoid Sp contribute to, or are associated with, respiratory failure among patients with CF remains unknown. Ot...

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Detalles Bibliográficos
Autores principales: Dennis, Evida A., Coats, Mamie T., Griffin, Sarah E., Hale, Joanetha Y., Novak, Lea, Briles, David E., Crain, Marilyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607445/
https://www.ncbi.nlm.nih.gov/pubmed/26469863
http://dx.doi.org/10.1371/journal.pone.0140335