hMRAPα, but Not hMRAP2, Enhances hMC4R Constitutive Activity in HEK293 Cells and This Is Not Dependent on hMRAPα Induced Changes in hMC4R Complex N-linked Glycosylation

MRAP1 but not MRAP2, is essential for melanocortin receptor 2 functional expression. Human MRAP1 splice variant (hMRAPα) and human MRAP2 (hMRAP2) also interact with the other melanocortin receptor subtypes in vitro, although the physiological significance of these interactions is unknown. Previously...

Descripción completa

Detalles Bibliográficos
Autores principales: Kay, Emma I., Botha, Rikus, Montgomery, Johanna M., Mountjoy, Kathleen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607451/
https://www.ncbi.nlm.nih.gov/pubmed/26469516
http://dx.doi.org/10.1371/journal.pone.0140320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607451/
https://www.ncbi.nlm.nih.gov/pubmed/26469516
http://dx.doi.org/10.1371/journal.pone.0140320

Ejemplares similares