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The Effector Domain of MARCKS Is a Nuclear Localization Signal that Regulates Cellular PIP2 Levels and Nuclear PIP2 Localization

Translocation to the nucleus of diacylglycerol kinase (DGK)– ζ is dependent on a sequence homologous to the effector domain of Myristoylated Alanine Rich C-Kinase Substrate (MARCKS). These data would suggest that MARCKS could also localize to the nucleus. A single report demonstrated immunofluoresce...

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Detalles Bibliográficos
Autores principales: Rohrbach, Timothy D., Shah, Nishi, Jackson, William P., Feeney, Erin V., Scanlon, Samantha, Gish, Robert, Khodadadi, Ryan, Hyde, Stephen O., Hicks, Patricia H., Anderson, Joshua C., Jarboe, John S., Willey, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607481/
https://www.ncbi.nlm.nih.gov/pubmed/26470026
http://dx.doi.org/10.1371/journal.pone.0140870