A Neutrophil Phenotype Model for Extracorporeal Treatment of Sepsis

Neutrophils play a central role in eliminating bacterial pathogens, but may also contribute to end-organ damage in sepsis. Interleukin-8 (IL-8), a key modulator of neutrophil function, signals through neutrophil specific surface receptors CXCR-1 and CXCR-2. In this study a mechanistic computational...

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Detalles Bibliográficos
Autores principales: Malkin, Alexander D., Sheehan, Robert P., Mathew, Shibin, Federspiel, William J., Redl, Heinz, Clermont, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607502/
https://www.ncbi.nlm.nih.gov/pubmed/26468651
http://dx.doi.org/10.1371/journal.pcbi.1004314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607502/
https://www.ncbi.nlm.nih.gov/pubmed/26468651
http://dx.doi.org/10.1371/journal.pcbi.1004314

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