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SNP Formation Bias in the Murine Genome Provides Evidence for Parallel Evolution

In this study, we show novel DNA motifs that promote single nucleotide polymorphism (SNP) formation and are conserved among exons, introns, and intergenic DNA from mice (Sanger Mouse Genomes Project), human genes (1000 Genomes), and tumor-specific somatic mutations (data from TCGA). We further chara...

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Detalles Bibliográficos
Autores principales: Plyler, Zackery E., Hill, Aubrey E., McAtee, Christopher W., Cui, Xiangqin, Moseley, Leah A., Sorscher, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607513/
https://www.ncbi.nlm.nih.gov/pubmed/26253317
http://dx.doi.org/10.1093/gbe/evv150