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SNP Formation Bias in the Murine Genome Provides Evidence for Parallel Evolution
In this study, we show novel DNA motifs that promote single nucleotide polymorphism (SNP) formation and are conserved among exons, introns, and intergenic DNA from mice (Sanger Mouse Genomes Project), human genes (1000 Genomes), and tumor-specific somatic mutations (data from TCGA). We further chara...
Autores principales: | Plyler, Zackery E., Hill, Aubrey E., McAtee, Christopher W., Cui, Xiangqin, Moseley, Leah A., Sorscher, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607513/ https://www.ncbi.nlm.nih.gov/pubmed/26253317 http://dx.doi.org/10.1093/gbe/evv150 |
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