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Immunization with Ty21a live oral typhoid vaccine elicits cross-reactive multifunctional CD8+ T cell responses against Salmonella enterica serovar Typhi, S. Paratyphi A and S. Paratyphi B in humans

Previously we have extensively characterized Salmonella enterica serovar Typhi (S. Typhi)-specific cell-mediated immune responses (CMI) in volunteers orally immunized with the licensed Ty21a typhoid vaccine. In this study we measured Salmonella-specific multifunctional (MF) CD8+ T cell responses to...

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Detalles Bibliográficos
Autores principales: Wahid, Rezwanul, Fresnay, Stephanie, Levine, Myron M., Sztein, Marcelo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607552/
https://www.ncbi.nlm.nih.gov/pubmed/25872480
http://dx.doi.org/10.1038/mi.2015.24