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Discovery and optimisation studies of antimalarial phenotypic hits
There is an urgent need for the development of new antimalarial compounds. As a result of a phenotypic screen, several compounds with potent activity against the parasite Plasmodium falciparum were identified. Characterization of these compounds is discussed, along with approaches to optimise the ph...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Editions Scientifiques Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607724/ https://www.ncbi.nlm.nih.gov/pubmed/26408453 http://dx.doi.org/10.1016/j.ejmech.2015.08.044 |