Modular Design of the Selectivity Filter Pore Loop in a Novel Family of Prokaryotic ‘Inward Rectifier’ (NirBac) channels

Potassium channels exhibit a modular design with distinct structural and functional domains; in particular, a highly conserved pore-loop sequence that determines their ionic selectivity. We now report the functional characterisation of a novel group of functionally non-selective members of the proka...

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Detalles Bibliográficos
Autores principales: Zubcevic, Lejla, Wang, Shizhen, Bavro, Vassiliy N., Lee, Sun-Joo, Nichols, Colin G., Tucker, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607889/
https://www.ncbi.nlm.nih.gov/pubmed/26470642
http://dx.doi.org/10.1038/srep15305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607889/
https://www.ncbi.nlm.nih.gov/pubmed/26470642
http://dx.doi.org/10.1038/srep15305

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