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Modular Design of the Selectivity Filter Pore Loop in a Novel Family of Prokaryotic ‘Inward Rectifier’ (NirBac) channels
Potassium channels exhibit a modular design with distinct structural and functional domains; in particular, a highly conserved pore-loop sequence that determines their ionic selectivity. We now report the functional characterisation of a novel group of functionally non-selective members of the proka...
Autores principales: | Zubcevic, Lejla, Wang, Shizhen, Bavro, Vassiliy N., Lee, Sun-Joo, Nichols, Colin G., Tucker, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607889/ https://www.ncbi.nlm.nih.gov/pubmed/26470642 http://dx.doi.org/10.1038/srep15305 |
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