EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism

The proteasome inhibitors Bortezomib (BZM) and MG132 trigger cancer cell death via induction of endoplasmic reticulum (ER) stress and unfolded protein response. Epigallocatechin gallate (EGCG), the most bioactive green tea polyphenol, is known to display strong anticancer properties as it inhibits p...

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Detalles Bibliográficos
Autores principales: Modernelli, Alice, Naponelli, Valeria, Giovanna Troglio, Maria, Bonacini, Martina, Ramazzina, Ileana, Bettuzzi, Saverio, Rizzi, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607952/
https://www.ncbi.nlm.nih.gov/pubmed/26471237
http://dx.doi.org/10.1038/srep15270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607952/
https://www.ncbi.nlm.nih.gov/pubmed/26471237
http://dx.doi.org/10.1038/srep15270

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