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Antigenically Modified Human Pluripotent Stem Cells Generate Antigen-Presenting Dendritic Cells
Human pluripotent stem cells (hPSCs) provide a promising platform to produce dendritic cell (DC) vaccine. To streamline the production process, we investigated a unique antigen-loading strategy that suits this novel platform. Specifically, we stably modified hPSCs using tumour antigen genes in the f...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608011/ https://www.ncbi.nlm.nih.gov/pubmed/26471005 http://dx.doi.org/10.1038/srep15262 |