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Novel insights from 3D models: the pivotal role of physical symmetry in epithelial organization

3D tissue culture models are utilized to study breast cancer and other pathologies because they better capture the complexity of in vivo tissue architecture compared to 2D models. However, to mimic the in vivo environment, the mechanics and geometry of the ECM must also be considered. Here, we studi...

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Detalles Bibliográficos
Autores principales: Kurup, Abhishek, Ravindranath, Shreyas, Tran, Tim, Keating, Mark, Gascard, Philippe, Valdevit, Lorenzo, Tlsty, Thea D., Botvinick, Elliot L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608012/
https://www.ncbi.nlm.nih.gov/pubmed/26472542
http://dx.doi.org/10.1038/srep15153