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Novel insights from 3D models: the pivotal role of physical symmetry in epithelial organization
3D tissue culture models are utilized to study breast cancer and other pathologies because they better capture the complexity of in vivo tissue architecture compared to 2D models. However, to mimic the in vivo environment, the mechanics and geometry of the ECM must also be considered. Here, we studi...
Autores principales: | Kurup, Abhishek, Ravindranath, Shreyas, Tran, Tim, Keating, Mark, Gascard, Philippe, Valdevit, Lorenzo, Tlsty, Thea D., Botvinick, Elliot L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608012/ https://www.ncbi.nlm.nih.gov/pubmed/26472542 http://dx.doi.org/10.1038/srep15153 |
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