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Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells

BACKGROUND: Neuroblastoma is the most common extracranial solid tumor of childhood. The heterogeneous microenvironment of solid tumors contains hypoxic regions associated with poor prognosis and chemoresistance. Hypoxia implicates the actin cytoskeleton through its essential roles in motility, invas...

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Detalles Bibliográficos
Autores principales: Glass, Joshua J., Phillips, Phoebe A., Gunning, Peter W., Stehn, Justine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608101/
https://www.ncbi.nlm.nih.gov/pubmed/26475688
http://dx.doi.org/10.1186/s12885-015-1741-8