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Eukaryotic G protein-coupled receptors as descendants of prokaryotic sodium-translocating rhodopsins

ABSTRACT: Microbial rhodopsins and G-protein coupled receptors (GPCRs, which include animal rhodopsins) are two distinct (super) families of heptahelical (7TM) membrane proteins that share obvious structural similarities but no significant sequence similarity. Comparison of the recently solved high-...

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Detalles Bibliográficos
Autores principales: Shalaeva, Daria N., Galperin, Michael Y., Mulkidjanian, Armen Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608122/
https://www.ncbi.nlm.nih.gov/pubmed/26472483
http://dx.doi.org/10.1186/s13062-015-0091-4