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Depletion of highly abundant proteins from human cerebrospinal fluid: a cautionary note
Affinity-based techniques, both for enrichment or depletion of proteins of interest, suffer from unwanted interactions between the bait or matrix material and molecules different from the original target. This effect was quantitatively studied by applying two common procedures for the depletion of a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608131/ https://www.ncbi.nlm.nih.gov/pubmed/26471478 http://dx.doi.org/10.1186/s13024-015-0050-7 |