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Depletion of highly abundant proteins from human cerebrospinal fluid: a cautionary note

Affinity-based techniques, both for enrichment or depletion of proteins of interest, suffer from unwanted interactions between the bait or matrix material and molecules different from the original target. This effect was quantitatively studied by applying two common procedures for the depletion of a...

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Detalles Bibliográficos
Autores principales: Günther, Ramona, Krause, Eberhard, Schümann, Michael, Blasig, Ingolf E., Haseloff, Reiner F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608131/
https://www.ncbi.nlm.nih.gov/pubmed/26471478
http://dx.doi.org/10.1186/s13024-015-0050-7