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Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER
BACKGROUND: Estrogen (17β-estradiol) promotes the survival and proliferation of breast cancer cells and its receptors represent important therapeutic targets. The cellular actions of estrogen are mediated by the nuclear estrogen receptors ERα and ERβ as well as the 7-transmembrane spanning G protein...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608161/ https://www.ncbi.nlm.nih.gov/pubmed/26470790 http://dx.doi.org/10.1186/s12885-015-1699-6 |