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Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER

BACKGROUND: Estrogen (17β-estradiol) promotes the survival and proliferation of breast cancer cells and its receptors represent important therapeutic targets. The cellular actions of estrogen are mediated by the nuclear estrogen receptors ERα and ERβ as well as the 7-transmembrane spanning G protein...

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Detalles Bibliográficos
Autores principales:	Zekas, Erin, Prossnitz, Eric R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608161/ https://www.ncbi.nlm.nih.gov/pubmed/26470790 http://dx.doi.org/10.1186/s12885-015-1699-6

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