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MiR-449a suppresses the epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by multiple targets

BACKGROUND: Increasing evidence indicates that Epithelial–mesenchymal transition (EMT) can be regulated by microRNAs (miRNAs). MiR-449a is a liver abundant miRNA. However, the role of miR-449a in the metastasis of hepatocellular carcinoma (HCC) remains largely unknown. METHODS: The expression levels...

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Detalles Bibliográficos
Autores principales: Chen, Shu-peng, Liu, Bao-xin, Xu, Jie, Pei, Xiao-feng, Liao, Yi-ji, Yuan, Feng, Zheng, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608176/
https://www.ncbi.nlm.nih.gov/pubmed/26471185
http://dx.doi.org/10.1186/s12885-015-1738-3