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High-level secretion of native recombinant human calreticulin in yeast

BACKGROUND: Calreticulin (CRT) resides in the endoplasmic reticulum (ER) and functions to chaperone proteins, ensuring proper folding, and intracellular Ca(2+) homeostasis. Emerging evidence shows that CRT is a multifunctional protein with significant roles in physiological and pathological processe...

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Detalles Bibliográficos
Autores principales:	Čiplys, Evaldas, Žitkus, Eimantas, Gold, Leslie I., Daubriac, Julien, Pavlides, Savvas C., Højrup, Peter, Houen, Gunnar, Wang, Wen-An, Michalak, Marek, Slibinskas, Rimantas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608220/ https://www.ncbi.nlm.nih.gov/pubmed/26471510 http://dx.doi.org/10.1186/s12934-015-0356-8

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