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Muscleblind-like 1 is required for normal heart valve development in vivo

BACKGROUND: Development of the valves and septa of the heart depends on the formation and remodeling of the endocardial cushions in the atrioventricular canal and outflow tract. These cushions are populated by mesenchyme produced from the endocardium by epithelial-mesenchymal transition (EMT). The e...

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Detalles Bibliográficos
Autores principales: Coram, Ryan J., Stillwagon, Samantha J., Guggilam, Anuradha, Jenkins, Michael W., Swanson, Maurice S., Ladd, Andrea N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608261/
https://www.ncbi.nlm.nih.gov/pubmed/26472242
http://dx.doi.org/10.1186/s12861-015-0087-4