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Muscleblind-like 1 is required for normal heart valve development in vivo
BACKGROUND: Development of the valves and septa of the heart depends on the formation and remodeling of the endocardial cushions in the atrioventricular canal and outflow tract. These cushions are populated by mesenchyme produced from the endocardium by epithelial-mesenchymal transition (EMT). The e...
Autores principales: | Coram, Ryan J., Stillwagon, Samantha J., Guggilam, Anuradha, Jenkins, Michael W., Swanson, Maurice S., Ladd, Andrea N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608261/ https://www.ncbi.nlm.nih.gov/pubmed/26472242 http://dx.doi.org/10.1186/s12861-015-0087-4 |
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