A comparison of the brief international cognitive assessment for multiple sclerosis and the brief repeatable battery in multiple sclerosis patients

BACKGROUND: Recently, a Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) has been developed as an international and standardized brief cognitive test, which is easily performed in everyday clinical practice for neuropsychological assessment in multiple sclerosis (MS). However...

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Autores principales: Niccolai, Claudia, Portaccio, Emilio, Goretti, Benedetta, Hakiki, Bahia, Giannini, Marta, Pastò, Luisa, Righini, Isabella, Falautano, Monica, Minacapelli, Eleonora, Martinelli, Vittorio, Incerti, Chiara, Nocentini, Ugo, Fenu, Giuseppe, Cocco, Eleonora, Marrosu, Maria Giovanna, Garofalo, Elisa, Ambra, Ferdinando Ivano, Maddestra, Maurizio, Consalvo, Marilena, Viterbo, Rosa Gemma, Trojano, Maria, Losignore, Nunzia Alessandra, Zimatore, Giovanni Bosco, Pietrolongo, Erika, Lugaresi, Alessandra, Pippolo, Lorena, Roscio, Marco, Ghezzi, Angelo, Castellano, Debora, Stecchi, Sergio, Amato, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608308/
https://www.ncbi.nlm.nih.gov/pubmed/26472052
http://dx.doi.org/10.1186/s12883-015-0460-8
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author Niccolai, Claudia
Portaccio, Emilio
Goretti, Benedetta
Hakiki, Bahia
Giannini, Marta
Pastò, Luisa
Righini, Isabella
Falautano, Monica
Minacapelli, Eleonora
Martinelli, Vittorio
Incerti, Chiara
Nocentini, Ugo
Fenu, Giuseppe
Cocco, Eleonora
Marrosu, Maria Giovanna
Garofalo, Elisa
Ambra, Ferdinando Ivano
Maddestra, Maurizio
Consalvo, Marilena
Viterbo, Rosa Gemma
Trojano, Maria
Losignore, Nunzia Alessandra
Zimatore, Giovanni Bosco
Pietrolongo, Erika
Lugaresi, Alessandra
Pippolo, Lorena
Roscio, Marco
Ghezzi, Angelo
Castellano, Debora
Stecchi, Sergio
Amato, Maria Pia
author_facet Niccolai, Claudia
Portaccio, Emilio
Goretti, Benedetta
Hakiki, Bahia
Giannini, Marta
Pastò, Luisa
Righini, Isabella
Falautano, Monica
Minacapelli, Eleonora
Martinelli, Vittorio
Incerti, Chiara
Nocentini, Ugo
Fenu, Giuseppe
Cocco, Eleonora
Marrosu, Maria Giovanna
Garofalo, Elisa
Ambra, Ferdinando Ivano
Maddestra, Maurizio
Consalvo, Marilena
Viterbo, Rosa Gemma
Trojano, Maria
Losignore, Nunzia Alessandra
Zimatore, Giovanni Bosco
Pietrolongo, Erika
Lugaresi, Alessandra
Pippolo, Lorena
Roscio, Marco
Ghezzi, Angelo
Castellano, Debora
Stecchi, Sergio
Amato, Maria Pia
author_sort Niccolai, Claudia
collection PubMed
description BACKGROUND: Recently, a Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) has been developed as an international and standardized brief cognitive test, which is easily performed in everyday clinical practice for neuropsychological assessment in multiple sclerosis (MS). However, we need to gather more information about this tool compared to other neuropsychological batteries. The aim of our study is to compare the performance of BICAMS and Brief Repeatable Battery (BRB) in MS subjects. METHODS: Tests of the BRB and BICAMS were administered to MS patients recruited from 11 Italian MS centres. Cognitive impairment (CI) was defined as the failure on at least two tests (scores below the fifth percentile) on the BRB and as the failure on at least one test of the BICAMS. The agreement between the performances on the two batteries was assessed through Cohen’s K statistic. Finally we calculated the effects sizes for each test of the two batteries using Cohen’s d. RESULTS: The two batteries were administered to 192 MS patients (142 women, 50 men; mean age 41.4 ± 10.8 years, mean education 12.3 ± 3.5 years). Mean scores of patients were lower compared to those of healthy subjects in all the cognitive measures examined. Forty-six MS patients were identified as impaired and 48 as unimpaired on both of the batteries, when the Symbol Digit Modalities Test (SDMT) was included in the analysis. Cohen’s K statistic was 0.46 which corresponds to a moderate accord. If the SDMT was excluded from the BRB, 37 MS patients were identified as impaired and 57 as unimpaired on both of the batteries. Cohen’s K statistic was 0.3 which corresponds to a poor accord. The SDMT, the Paced Auditory Serial Addition Test (PASAT) 3 and 2 yielded higher d values (SDMT 0.83, PASAT 3 0.65, PASAT 2 0.84). CONCLUSIONS: This study confirms the feasibility of BICAMS in everyday clinical practice for the identification of CI and highlights the good psychometric properties of the SDMT.
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spelling pubmed-46083082015-10-17 A comparison of the brief international cognitive assessment for multiple sclerosis and the brief repeatable battery in multiple sclerosis patients Niccolai, Claudia Portaccio, Emilio Goretti, Benedetta Hakiki, Bahia Giannini, Marta Pastò, Luisa Righini, Isabella Falautano, Monica Minacapelli, Eleonora Martinelli, Vittorio Incerti, Chiara Nocentini, Ugo Fenu, Giuseppe Cocco, Eleonora Marrosu, Maria Giovanna Garofalo, Elisa Ambra, Ferdinando Ivano Maddestra, Maurizio Consalvo, Marilena Viterbo, Rosa Gemma Trojano, Maria Losignore, Nunzia Alessandra Zimatore, Giovanni Bosco Pietrolongo, Erika Lugaresi, Alessandra Pippolo, Lorena Roscio, Marco Ghezzi, Angelo Castellano, Debora Stecchi, Sergio Amato, Maria Pia BMC Neurol Research Article BACKGROUND: Recently, a Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) has been developed as an international and standardized brief cognitive test, which is easily performed in everyday clinical practice for neuropsychological assessment in multiple sclerosis (MS). However, we need to gather more information about this tool compared to other neuropsychological batteries. The aim of our study is to compare the performance of BICAMS and Brief Repeatable Battery (BRB) in MS subjects. METHODS: Tests of the BRB and BICAMS were administered to MS patients recruited from 11 Italian MS centres. Cognitive impairment (CI) was defined as the failure on at least two tests (scores below the fifth percentile) on the BRB and as the failure on at least one test of the BICAMS. The agreement between the performances on the two batteries was assessed through Cohen’s K statistic. Finally we calculated the effects sizes for each test of the two batteries using Cohen’s d. RESULTS: The two batteries were administered to 192 MS patients (142 women, 50 men; mean age 41.4 ± 10.8 years, mean education 12.3 ± 3.5 years). Mean scores of patients were lower compared to those of healthy subjects in all the cognitive measures examined. Forty-six MS patients were identified as impaired and 48 as unimpaired on both of the batteries, when the Symbol Digit Modalities Test (SDMT) was included in the analysis. Cohen’s K statistic was 0.46 which corresponds to a moderate accord. If the SDMT was excluded from the BRB, 37 MS patients were identified as impaired and 57 as unimpaired on both of the batteries. Cohen’s K statistic was 0.3 which corresponds to a poor accord. The SDMT, the Paced Auditory Serial Addition Test (PASAT) 3 and 2 yielded higher d values (SDMT 0.83, PASAT 3 0.65, PASAT 2 0.84). CONCLUSIONS: This study confirms the feasibility of BICAMS in everyday clinical practice for the identification of CI and highlights the good psychometric properties of the SDMT. BioMed Central 2015-10-15 /pmc/articles/PMC4608308/ /pubmed/26472052 http://dx.doi.org/10.1186/s12883-015-0460-8 Text en © Niccolai et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Niccolai, Claudia
Portaccio, Emilio
Goretti, Benedetta
Hakiki, Bahia
Giannini, Marta
Pastò, Luisa
Righini, Isabella
Falautano, Monica
Minacapelli, Eleonora
Martinelli, Vittorio
Incerti, Chiara
Nocentini, Ugo
Fenu, Giuseppe
Cocco, Eleonora
Marrosu, Maria Giovanna
Garofalo, Elisa
Ambra, Ferdinando Ivano
Maddestra, Maurizio
Consalvo, Marilena
Viterbo, Rosa Gemma
Trojano, Maria
Losignore, Nunzia Alessandra
Zimatore, Giovanni Bosco
Pietrolongo, Erika
Lugaresi, Alessandra
Pippolo, Lorena
Roscio, Marco
Ghezzi, Angelo
Castellano, Debora
Stecchi, Sergio
Amato, Maria Pia
A comparison of the brief international cognitive assessment for multiple sclerosis and the brief repeatable battery in multiple sclerosis patients
title A comparison of the brief international cognitive assessment for multiple sclerosis and the brief repeatable battery in multiple sclerosis patients
title_full A comparison of the brief international cognitive assessment for multiple sclerosis and the brief repeatable battery in multiple sclerosis patients
title_fullStr A comparison of the brief international cognitive assessment for multiple sclerosis and the brief repeatable battery in multiple sclerosis patients
title_full_unstemmed A comparison of the brief international cognitive assessment for multiple sclerosis and the brief repeatable battery in multiple sclerosis patients
title_short A comparison of the brief international cognitive assessment for multiple sclerosis and the brief repeatable battery in multiple sclerosis patients
title_sort comparison of the brief international cognitive assessment for multiple sclerosis and the brief repeatable battery in multiple sclerosis patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608308/
https://www.ncbi.nlm.nih.gov/pubmed/26472052
http://dx.doi.org/10.1186/s12883-015-0460-8
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