Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs Suppress Inflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation and Reduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats

The immune system plays a fundamental role in both the development and pathobiology of stroke. Inflammasomes are multiprotein complexes that have come to be recognized as critical players in the inflammation that ultimately contributes to stroke severity. Inflammasomes recognize microbial and host-d...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Mou, Yongshan, Bernstock, Joshua D., Klimanis, Dace, Wang, Sixian, Spatz, Maria, Maric, Dragan, Johnson, Kory, Klinman, Dennis M., Li, Xiaohong, Li, Xinhui, Hallenbeck, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608557/
https://www.ncbi.nlm.nih.gov/pubmed/26473731
http://dx.doi.org/10.1371/journal.pone.0140772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608557/
https://www.ncbi.nlm.nih.gov/pubmed/26473731
http://dx.doi.org/10.1371/journal.pone.0140772

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