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IL-22/STAT3-Induced Increases in SLURP1 Expression within Psoriatic Lesions Exerts Antimicrobial Effects against Staphylococcus aureus

BACKGROUND: SLURP1 is the causal gene for Mal de Meleda (MDM), an autosomal recessive skin disorder characterized by diffuse palmoplantar keratoderma and transgressive keratosis. Moreover, although SLURP1 likely serves as an important proliferation/differentiation factor in keratinocytes, the possib...

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Detalles Bibliográficos
Autores principales: Moriwaki, Yasuhiro, Takada, Kiyoko, Nagasaki, Toshinori, Kubo, Natsuki, Ishii, Tomohiro, Kose, Kazuaki, Kageyama, Taihei, Tsuji, Shoutaro, Kawashima, Koichiro, Misawa, Hidemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608685/
https://www.ncbi.nlm.nih.gov/pubmed/26474319
http://dx.doi.org/10.1371/journal.pone.0140750