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Identifying the Role of E2 Domains on Alphavirus Neutralization and Protective Immune Responses

BACKGROUND: Chikungunya virus (CHIKV) and other alphaviruses are the etiologic agents of numerous diseases in both humans and animals. Despite this, the viral mediators of protective immunity against alphaviruses are poorly understood, highlighted by the lack of a licensed human vaccine for any memb...

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Detalles Bibliográficos
Autores principales: Weger-Lucarelli, James, Aliota, Matthew T., Kamlangdee, Attapon, Osorio, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608762/
https://www.ncbi.nlm.nih.gov/pubmed/26473963
http://dx.doi.org/10.1371/journal.pntd.0004163