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Release of a Poorly Soluble Drug from Hydrophobically Modified Poly (Acrylic Acid) in Simulated Intestinal Fluids

A large part of new pharmaceutical substances are characterized by a poor solubility and high hydrophobicity, which might lead to a difference in drug adsorption between fasted and fed patients. We have previously evaluated the release of hydrophobic drugs from tablets based on Pemulen TR2 and showe...

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Detalles Bibliográficos
Autores principales: Knöös, Patrik, Svensson, Anna V., Ulvenlund, Stefan, Wahlgren, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608824/
https://www.ncbi.nlm.nih.gov/pubmed/26473964
http://dx.doi.org/10.1371/journal.pone.0140709