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Imaging cerebral tryptophan metabolism in brain tumor-associated depression

BACKGROUND: Depression in patients with brain tumors is associated with impaired quality of life and shorter survival. Altered metabolism of tryptophan to serotonin and kynurenine metabolites may play a role in tumor-associated depression. Our recent studies with alpha[(11)C]methyl-L-tryptophan (AMT...

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Detalles Bibliográficos
Autores principales: Bosnyák, Edit, Kamson, David O., Behen, Michael E., Barger, Geoffrey R., Mittal, Sandeep, Juhász, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608955/
https://www.ncbi.nlm.nih.gov/pubmed/26475140
http://dx.doi.org/10.1186/s13550-015-0136-9