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Mesenchymal stem cells suppress neuronal apoptosis and decrease IL-10 release via the TLR2/NFκB pathway in rats with hypoxic-ischemic brain damage

BACKGROUND: Hypoxic–ischemic brain damage (HIBD) is a major cause of infant mortality and neurological disability in children. Many studies have demonstrated that mesenchymal stem cell (MSC) transplantation facilitates the restoration of the biological function of injured tissue following HIBD via i...

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Detalles Bibliográficos
Autores principales: Gu, Yan, Zhang, Yun, Bi, Yang, Liu, Jingjing, Tan, Bin, Gong, Min, Li, Tingyu, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609057/
https://www.ncbi.nlm.nih.gov/pubmed/26475712
http://dx.doi.org/10.1186/s13041-015-0157-3